LISTEN TO THE EXPERTS

Christopher Mantyh, MD
Colorectal surgeon

Associate Professor of Surgery/Chief, Gastrointestinal and Colorectal Surgery at Duke University Medical Center

Learn about Dr. Mantyh's clinical use of OFIRMEV and link to hear other experiences from your peers

Mean pain relief scores in total hip or knee replacement surgery for OFIRMEV vs placebo

LESS PAIN

Take a closer look at the clinical data from
Pain Study 1

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Sinatra et al. (Pain Study 1)
Randomized, double-blind, placebo-controlled, single- and repeated-dose 24-h study (n=101). Patients received OFIRMEV 1 g + PCA morphine or placebo + PCA morphine the morning following total hip or knee replacement surgery. Primary endpoint: pain relief measured on a 5-point verbal scale over 6 h. Morphine rescue was administered as needed.

Reduction in morphine consumption in total hip or knee replacement surgery for OFIRMEV vs placebo

LESS OPIOIDS

See how OFIRMEV + PCA morphine significantly reduced morphine consumption vs placebo + PCA morphine1

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Sinatra et al. (Pain Study 1)
Randomized, double-blind, placebo-controlled, single- and repeated-dose 24-h study (n=101). Patients received OFIRMEV 1 g + PCA morphine or placebo + PCA morphine the morning following total hip or knee replacement surgery. Primary endpoint: pain relief measured on a 5-point verbal scale over 6 h. Morphine rescue was administered as needed.

OFIRMEV FROM THE START

See how pre-op administration of
IV acetaminophen 1 g demonstrated
greater reductions in post-op pain intensity
scores vs placebo5

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Arici et al.
Randomized, placebo‐controlled, parallel-group, single-site study. Patients
scheduled for total abdominal hysterectomy received IV acetaminophen 1 g
30 minutes prior to induction (pre-op), IV acetaminophen 1 g prior to skin closure
(intra-op), or placebo. PCA morphine was available to all patients. Pain intensity,
based on VAS, at rest and with movement, sedation, and total morphine
consumption were measured at 15 and 30 minutes, 1, 2, 4, 8, 12, and 24 h.

ADMINISTER PRE-OP, THEN SCHEDULE Q6H

Review more dosing information...